Reverse-aging on the Skin with Biosynthetic Human Growth Factors as Bona fide Cosmetic Actives
Biosynthetic human protein (polypeptide/oligopeptide) growth factors were introduced to the
cosmetic field in the 1990’s by a plastic surgeon, Gregory L.(Bays) Brown, MD, who later founded RéVive
Skincare in 1997. Abundance of previous studies, however, attested polypeptides, most of them
hydrophilic, are too big to penetrate the hydrophobic stratum corneum (the epidermal keratin layer) or to
get efficiently delivered to the deeper layers of epidermis or dermis of the intact skin.
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